Would any of those introspective, guitar strumming, female singer-songwriters featured on "Grey's Anatomy" even exist without Ani DiFranco? Maybe. But they certainly have Ani to thank for preparing the world for righteous babes who make good folk for the masses. Tonight, DiFranco (left) is at the Orpheum Theatre to promote "Canon," her two-disc retrospective. Listen for the old song she updated for the CD, "Both Hands." The show starts at 8. Tickets: $36, $39. Orpheum, 1 Hamilton Place, 617-679-0810. ticketmaster.com
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