Nominees:
Winner is marked with an asterisk (*) and highlighted in bold.

Julia Louis-Dreyfus as Christine, CBS's "The New Adventures of Old Christine"

Christina Applegate as Samantha Newly, ABC's "Samantha Who?"

Sarah Silverman as Sarah Silverman, Comedy Centrals' "The Sarah Silverman Program"

Tina Fey as Liz Lemon, NBC's "30 Rock" (pictured)

*Toni Collette as Tara Gregson, Showtime's "United States Of Tara"

Mary-Louise Parker as Nancy Botwin, Showtime's "Weeds"