Lorenzo Odone, subject of film 'Lorenzo's Oil'
WASHINGTON - The man whose parents' battle to save him from a nerve disease was told in the movie "Lorenzo's Oil" died yesterday at his home in Virginia.
Lorenzo Odone, who doctors had predicted would not live past childhood, died one day after his 30th birthday, said his father, Augusto. Lorenzo Odone became infected with aspiration pneumonia recently after getting food stuck in his lungs, his father said.
Mr. Odone was found at age 6 to have adrenoleukodystrophy, or ALD. His doctors told his parents the disease - caused by a genetic mutation that causes the neurological system to break down - would lead to death in two years.
The disease leads to the accumulation of substances called very long chain fatty acids in cells, which damages the material that coats nerve fibers in the brain.
Susan Sarandon and Nick Nolte starred as Michaela and Augusto Odone in 1992's "Lorenzo's Oil," which recounted their efforts to formulate the oil they said helped their son fight the disease, despite lacking scientific backgrounds. Sarandon earned an Academy Award nomination.
A study published in 2005, based on research with 84 boys, showed that a treatment made from olive and rapeseed oils - patented by Augusto Odone - can prevent onset of the disease's symptoms for most boys who receive an ALD diagnosis.
Odone plans to take his son's ashes to New York to mix them with those of his wife, who died in 2000. Then, Odone said, he will move back to his native Italy. 