Partners HealthCare System Inc. is in talks to acquire South Shore Hospital in Weymouth, one of the largest remaining independent hospitals in the Boston area, in a deal that would reshape the competitive landscape in the region’s health care market, according to two health care professionals who have been briefed by the parties on the negotiations. The 318-bed regional hospital serves a swath of southeastern Massachusetts extending from Quincy to Taunton to Cape Cod.
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