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The 18th Annual 2006 Globe 100 | The Best of Massachusetts Business Index of coverage Globe 100 chart
1. Akamai Inc.
2. American Science
3. Genzyme
4. Affiliated Managers
5. First Marblehead
No. 6-10
Complete 2006
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The bulls

Ranked by percentage change in stock price.
RankCompanyPrice on 3/31/06Price on 3/31/05Change (%)
1 BTU International $16.43 $3.32 394.9
2 Advanced Magnetics $38.25 $8.78 335.6
3 Neurometrix $38.94 $9.55 307.7
4 Vertex Pharmaceuticals $36.59 $9.36 290.9
5 Hologic $55.35 $15.94 247.3
6 Nuance Communications $11.81 $3.72 217.5
7 Akamai Technologies $32.89 $12.73 158.4
8 Smith & Wesson Holding Corp. $6.05 $2.41 151
9 Panacos Pharmaceuticals $7.56 $3.02 150.3
10 Bitstream $7.43 $3.05 143.6
11 Candela Corp. $21.60 $8.92 142.2
12 Alnylam Pharmaceuticals $17.59 $7.33 140
13 Momenta Pharmaceuticals $19.66 $8.47 132.1
14 Indevus Pharmaceuticals $6.20 $2.78 123
15 Aspen Technology $12.65 $5.68 122.7
16 Perini Corp. $30.37 $13.79 120.2
17 Evergreen Solar $15.40 $7.07 117.8
18 Cubist Pharmaceuticals $22.97 $10.62 116.3
19 Alkermes $22.05 $10.38 112.4
20 Color Kinetics $21.18 $10.08 110.1
21 American Science and Engineering $93.40 $44.71 108.9
22 Viisage Technology $17.51 $8.43 107.8
23 NetScout Systems $9.10 $4.45 104.5
24 NMT Medical $16.18 $8.20 97.3
25 Interleukin Genetics Inc. $7.15 $3.65 95.9
NOTE: Company stock must have traded at $2 or higher per share on March 31, 2005, and must have traded on March 31, 2006.
SOURCE: Standard & Poor's Compustat
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