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The 18th Annual 2006 Globe 100 | The Best of Massachusetts Business Index of coverage Globe 100 chart
1. Akamai Inc.
2. American Science
3. Genzyme
4. Affiliated Managers
5. First Marblehead
No. 6-10
Complete 2006
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Wall Street darlings

Ranked by ratio of market value to revenue.
RankCompany2005 revenue (millions)Market value (millions)Market value to revenue
1 Oxigene <$0.1 $107.4 107,436.1
2 Interleukin Genetics Inc. <$0.1 $127.5 5,543.8
3 Point Therapeutics $0.2 $108.8 676
4 Panacos Pharmaceuticals $1.0 $341.1 325.1
5 Ariad Pharmaceuticals $1.2 $360.6 296.3
6 Pressure BioSciences $0.1 $11.6 109.8
7 Beacon Power Corp. $1.5 $108.5 73
8 NitroMed $6.0 $425.2 70.3
9 Ibis Technology Corp. $0.6 $37.6 62.4
10 Alnylam Pharmaceuticals $5.7 $355.8 62.2
NOTE: Company stock must have been traded on Dec. 30, 2005, with a price of $1 a share or higher, and a market value of $1 million or higher.
SOURCE: Standard & Poor's Compustat
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