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Top biotech companies

Nationwide, the industry had its worst showing in six years. But in Massachusetts, five new biotechs went public, and the Bloomberg/Boston Globe Life Sciences index rose 8.6 percent. Billionaire investor Carl Ichan took note, buying Genzyme and Biogen Idec stakes. Ranked by revenue in 2007.

	Company	Revenue (millions)	Change (percent)
1	Genzyme Corp.	$3,813.5	19.7
2	Biogen Idec	$3,171.6	18.2
3	Millipore Corp.	$1,531.6	22.0
4	Waters Corp.	$1,473.0	15.1
5	Charles River Laboratories International	$1,230.6	16.3
6	Sepracor	$1,225.2	3.6
7	Bruker Corp.	$547.6	25.6
8	Millennium Pharmaceuticals	$527.5	8.4
9	Cubist Pharmaceuticals	$294.6	51.3
10	Alkermes	$243.2	6.3

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