2010 Globe 100 - The Best of Massachusetts Business

Largest profit margin

Ranked by profit margin in 2009.
Rank Company Revenue (millions) Net income (millions) Profit margin (percent)
1 Combinatorx $17.3 $15.4 89.1
2 Synta Pharmaceuticals Corp. $144.2 $79.1 54.8
3 Sonesta International Hotels Corp. $60.5 $25.3 41.8
4 Hingham Institution for Savings $27.5 $8.0 29.2
5 Hittite Microwave Corp. $163.0 $46.2 28.3
6 Brookline Bancorp $78.3 $19.2 24.5
7 LSB Corp. $21.7 $5.0 23.2
8 Biogen Idec $4,377.3 $970.1 22.2
9 Idera Pharmaceuticals $34.5 $7.5 21.9
10 Waters Corp. $1,498.7 $323.3 21.6
SOURCE: Capital IQ, a Standard & Poor's business