2011 Globe 100

Largest losses

Ranked by net income from continuing operations in 2010.
Rank Company Net income (millions) Change (percent)
1 Boston Scientific Corp. -$1,065.0 -3.9
2 Alere -1,017.3 -3,117.3
3 Vertex Pharmaceuticals -754.6 -17.5
4 Evergreen Solar -465.4 -74.8
5 Charles River Laboratories International -336.7 -394.2
6 A123 Systems -152.6 -77.9
7 Aspen Technology -81.5 -143.8
8 Smith & Wesson Holding Corp. -81.2 -318.0
9 AMAG Pharmaceuticals -81.2 13.1
10 Hologic -78.0 96.5
SOURCE: Compustat