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A drug's journey from idea to reality

Years of tests, setbacks bridged a curious observation in a hamster and the approval of a diabetes treatment

The Syrian hamster, which can modulate its metabolism as the seasons changes, was the inspiration behind VeroScience's Cycloset, which is used to treat type 2 diabetes. The Syrian hamster, which can modulate its metabolism as the seasons changes, was the inspiration behind VeroScience's Cycloset, which is used to treat type 2 diabetes. (istockphoto.com)
By Carolyn Y. Johnson
Globe Staff / May 7, 2009

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TIVERTON, R.I. - Anthony Cincotta hit bottom a little over a decade ago. The biotechnology start-up he had cofounded and built into a publicly traded company was spiraling out of his control. His older brother, Manny, an inspiration and business partner, was fighting leukemia that would soon take his life. And the FDA had just shot down the diabetes drug ... (Full article: 1012 words)

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