JetBlue Airways will start flying between Boston and Houston on July 25, the carrier’s 49th destination out of Logan International Airport.

Logan’s biggest airline will make the trip to William P. Hobby Airport twice a day, with an introductory sale price starting at $100 round trip for travel between Sept. 3 and Oct. 9.

Currently, United is the only carrier that flies nonstop from Boston to Houston, landing at the larger George Bush Intercontinental Airport.

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JetBlue operates more than 100 flights a day out of Logan and plans to expand to 150.

“JetBlue is committed to giving its customers more for less, which is particularly true for our new route to Houston, the first regularly scheduled service between these two airports,” Dennis Corrigan, JetBlue’s vice president of sales and revenue management, said in a statement.