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Regulators are investigating complaints that power-assisted brakes can fail at times in Camry gas-electric hybrids.
The probe covers about 30,000 of the mid-size cars from the 2007 and 2008 model years.
The National Highway Traffic Safety Administration said it has 59 complaints about intermittent loss of power-brake assist. The agency said the problem happens without warning. It causes increased stopping distances and requires more pedal pressure to stop the car.
Two crashes have been reported, but no injuries. The agency said 24 incidents happened at speeds of 40 miles per hour or more.
Investigators will try to find the cause and determine if the cars should be recalled.
Toyota spokesman John Hanson said the company is cooperating with the NHTSA.