He can, but...
While his 22 TDs in 6 games is amazing, what he has to accomplish the rest of the way is still extremely formidable.
The pace he has to keep up over these last 10 games is a rate that has been accomplished only 3 times in NFL history over a season. Brady, himself and Marino are the only three QBs to throw TDs at that frequently for a season.
Brady had 21 over the first 6 games in 2007 (PM has 22 at the moment.). Interestingly, Brady did not have a game under 3 TDs in the first 6 and Manning has a 2 TD outing against, of all teams, the Jags. His record tying opener against the Ravens has shot PM's TD rate into the stratosphere, but since then he has not quite been on a record pace.
While the Denver schedule has been very soft early (having played half their games against the 3 worst D's in the NFL) they still have to play the Pats and also play the Chiefs twice. Those aren't the cupcake D's they have faced so far. The weather only gets worse and factors such as injuries, clinching playoff spots and rest can become a factor as the season advances to a conclusion.
This should be an interesting sideshow to keep an eye on. It may very well come down to the wire. If he can do this, it will be an astounding accomplishment, especially considering his age, the schedule notwithstanding.