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The Boston Globe OnlineBoston.com Boston Globe Online / Archives

STUDY: LARGE DOSES OF VITAMIN C DON'T COMBAT CANCER

Author: By Judy Foreman, Globe Staff

Date: Thursday, January 17, 1985
Page: 8
Section: NATIONAL/FOREIGN

Linus Pauling - the Nobel prize winning chemist who has championed taking mega-doses of vitamin C to combat cancer - is wrong, according to a study published today.

That is the conclusion reached by Mayo Clinic and Mayo Foundation researchers who found that patients suffering from advanced cancer of the colon and rectum could not, as Pauling has claimed, prolong their survival or reverse the course of their tumors by taking large doses of vitamin C.

One hundred patients suffering from colorectal cancer which had spread to the rest of their bodies were given either 10 grams - a large dose - of vitamin C or a dummy medication daily, in a carefully controlled study. Until the study was over, neither patients nor doctors knew who was getting the vitamin and who received the inert substance, or placebo.

There was no significant difference in their survival rates, according to a report in the New England Journal of Medicine.

Although his study focused on only one type of cancer, said the clinic's Dr. Charles G. Moertel, he doubted that vitamin C would be any more effective against other types of cancer.

Pauling could not be reached by telephone yesterday.

None of the patients studied by Moertel's group had received chemotherapy, which is ineffective against colorectal cancer. This, the researchers noted, was an important consideration because Pauling hypothesized that vitamin C might not work if the body's natural defenses had already been weakened by chemotherapy.

FOREMA;01/16,14:39 LDRISC;01/17,14:27 VITAMI17


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