Charnan Bray, an ESL teacher who lives in Waltham, is a newcomer. She considers herself an on-again off-again meditator who wants to become more serious about her practice. She went through a divorce last year and is looking for a way to become more mindful and reduce the stress in her life.

Hannah Fairbairn of Belmont, a long-time member of the center, has been meditating for about 30 years. She turned to meditation shortly after she suffered a detached retina and began losing her eyesight. “I’m as sane as I am today not the least because of meditation,” she said.

Since Herbert Benson, the cardiologist and author of the groundbreaking 1975 book “The Relaxation Response,” first began pioneering mind-body research 40 years ago, numerous scientific studies have offered evidence for both Bray’s hopes and Fairbairn’s experience. Researchers at universities across the world have reported positive results from meditation in a wide range of ailments, including high blood pressure, stroke risk, heart disease, weight management, chronic pain, and mental health.

The 2007 National Health Interview Survey found that 20 million US adults had turned to meditation for health reasons in the previous year.

This consumer interest, along with the potential public health impact of meditation, has helped spur research into its effectiveness. Since 2002, the government’s National Center for Complementary and Alternative Medicine has funded about $57.7 million in scientific research into meditation, according to statistics provided by the office.

Last April, the International Symposia for Contemplative Studies, a first-ever conference of researchers, scholars, and students in the field, drew 720 participants from all over the world.

Why such scientific interest in meditation?

“Because we are all stressed out,” said Sara Lazar, a neuroscientist at Mass. General and a noted researcher in the field. “I think we’re finding evidence, that, yeah, meditation is not just a bunch of hocus pocus.”

Early research focused on the health benefits of stress reduction from meditation, but in recent years, neuroscientists like Lazar have begun using magnetic resonance imaging to show that meditation can make actual structural changes in the brain.

In a new imaging study released this fall, a team of researchers from Mass. Generall, Boston University, and Emory University, among others, reported that an eight-week meditation course can have measurable and enduring effects on how the brain functions, even when someone is not actively meditating.

In a 2005 imaging study at Mass. General led by Lazar, researchers scanned the brains of experienced meditators and found they had thicker gray matter than a control group of non-meditators. The gray matter thickened in regions involved in attention and sensory processing, showing evidence of cortical plasticity ­— the ability of the brain to adapt and regenerate as a result of a person’s experience

People who meditated, “weren’t just sitting there spacing out,” says Lazar. “Something very specific was happening to their brain.”

To address criticism that people with thickened gray matter in those areas might simply be attracted to meditation, researchers conducted a follow-up study. They scanned the brains of 16 people new to meditation before and after an eight-week program in which they meditated an average of 30 minutes per day. These were compared with brain scans of a control group of 17 people.

Researchers found that the meditators had significant density changes in the hippocampus and other brain structures related to learning, memory, self-awareness, and empathy. Another change that was noted in the meditating group was a decrease in the density of gray matter in the amygdala, which is correlated with a decline in stress, Lazar said.

At the UCLA Laboratory of Neuro Imaging in California, researchers released a study in March suggesting that meditation didn’t just thicken gray matter, but also increased the number of folds in the cortex — called gyrification.