A Springfield woman, two of her adult children, and a Connecticut man were killed in a car crash in Portland, Conn., early Saturday morning, police said. Another daughter, 18, was critically injured.

A Honda Civic going south on Rose Hill Road hit a concrete support under a bridge shortly before 3 a.m., Portland police Sergeant Scott D. Cunningham said.

Police and fire officials pronounced three dead at the scene: Ivette Amaro, 42; her son Pedro Duprey, 24; and Ramon Ruiz, a 30-year-old from Hartford, Conn., who Cunningham said was not related to the others.

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Amaro’s daughter, 20-year-old Andrea Caraballo of Springfield, was pronounced dead at Middlesex Hospital in Middletown, Conn. Another daughter, 18-year-old Juniarys Caraballo, was in critical condition late Saturday afternoon at Hartford Hospital, said Tina Varona, a hospital spokeswoman.

Because Juniarys Caraballo and Duprey were thrown out of the car during the crash, police are not sure who was driving, Cunningham said.

The cause of the crash is under investigation, Cunningham said.