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Local researchers win grants to explore human genome

Posted by Elizabeth Cooney October 9, 2007 05:24 PM

Two local researchers have received government grants to explore the organization and function of the human genome, part of an expansion of a project that already has shown the genome to be far more complex than previously thought.

Dr. Bradley Bernstein of the Broad Institute of MIT and Harvard and Zhiping Weng of Boston University are among principal investigators in the ENCyclopedia Of DNA Elements, or ENCODE, a project funded by the National Human Genome Research Institute. The insititute announced more than $80 million in grants today.

Bernstein has won $4.8 million over four years to study proteins important in DNA packaging in human cells. Weng will receive $1.5 million over three years to identify binding sites in regions of DNA that guide how genes are transcribed.

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Elizabeth Cooney covers health for the Worcester Telegram & Gazette. She previously reported on business and was an editor at the paper. Earlier in her career, she edited medical books and journals at Little, Brown, and worked for Boston magazine.

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