Today's Globe: Atrius shakeup, big bellies and dementia, nursing-home restraints, stent testing, Dr. Louis A. Selverstone

In a sweeping housecleaning six weeks after the resignation of its chief executive, Atrius Health of Newton has gotten rid of or rearranged many of its top managers and eliminated several key positions.

People who have big bellies in their 40s are much more likely to get Alzheimer's disease and other forms of dementia in their 70s, according to new research that links middle-age spread to fading minds for the first time.

The use of physical restraints on nursing home patients declined nearly 40 percent nationally in recent years as the federal government, states, and the nursing home industry placed greater emphasis on eliminating what once was a common practice.

The Food and Drug Administration said companies developing drug-coated stents should undertake new testing to identify the medicine used and show how it breaks up in the body (sixth item).

Dr. Louis A. Selverstone, a doctor who practiced internal medicine at Mount Auburn Hospital for 35 years, died March 17 of congestive heart failure at the Park Avenue Nursing Center in Arlington. He was 87 and spent most of his life in Boston (second item).