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Boston groups score prostate cancer research funds

Posted by Elizabeth Cooney  June 5, 2008 10:45 AM
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Four research teams based in Boston are among eight groups that have garnered $19 million in grants from a foundation focused on discovering new treatments for recurrent prostate cancer.

The Prostate Cancer Foundation, a philanthropy based in Santa Monica, Calif., announced its 2008 Challenge Awards, which will be distributed to each program in three annual payments of $500,000 to $1 million.

The lead investigators from Boston, their institutions, and their projects are:

Dr. Steven P. Balk, Beth Israel Deaconess Medical Center, and Dr. Peter S. Nelson, Fred Hutchinson Cancer Research Center, University of Washington: studying the reduction of androgens, or testosterone hormones, in tumor tissues from patients who are taking a new form of androgen-production inhibitor.

Dr. Levi A. Garraway, Dana-Farber Cancer Institute, Broad Institute of Harvard and MIT; Dr. Todd R. Golub, Broad Institute; Dr. William C. Hahn, Dana-Farber Cancer Institute, Broad Institute: using genetic methods to discover new drugs to target cancer-promoting factors in normal prostate cells.

Dr. Daniel Haber, Massachusetts General Hospital: refining a system to measure tumor cells in patients' blood that would signal disease progression and improve treatment choices.

Dr. Matthew R. Smith, Massachusetts General Hospital: examining the side effects of androgen-reduction treatments for advanced prostate cancer -- obesity, diabetes, bone fractures, and heart disease -- and how to limit them with exercise, nutrition, and new medications.

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About white coat notes

White Coat Notes covers the latest from the health care industry, hospitals, doctors offices, labs, insurers, and the corridors of government. Chelsea Conaboy previously covered health care for The Philadelphia Inquirer. Write her at cconaboy@boston.com. Follow her on Twitter: @cconaboy.
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