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UMass AIDS vaccine researchers win $18m grant

Posted by Elizabeth Cooney September 28, 2009 03:35 PM

University of Massachusetts Medical School scientists who began human testing of an AIDS vaccine five years ago have won two five-year grants totaling $18 million to further their research.

Dr. Shan Lu, professor of medicine and biochemistry and molecular pharmacology at UMass and a specialist in vaccine development, will lead both projects. One seeks to develop protective antibodies that will target the virus where it binds to human immune cells and the other will look further into the cocktail of viral antigens they tested in phase 1 human trials. The funding comes from the National Institute of Allergy and Infectious Diseases.

Creating an AIDS vaccine has been seen as an almost insurmountable challenge, given the poor results to date. Last week some encouraging news emerged from a massive trial in Thailand where a vaccine met limited success.

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Elizabeth Cooney is a former health reporter for the Worcester Telegram & Gazette, where she also was a business reporter and an editor. Earlier in her career, she edited medical books and journals at Little, Brown, and worked for Boston magazine.

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