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Regina’s Bakery, which opened during the summer of 2012 in the midst of the Dedham Square improvement project, closed last week. In an announcement on the bakery’s Facebook page on Jan. 26, the owners said that the months of construction and the lack of advertising made it difficult for them to maintain their business. Amy Haelsen, executive director of Dedham Square Circle, said in an interview Wednesday the Knights of Columbus would be fielding inquiries about the space in their building. Haelsen said she was at the bakery often and that the business closing wasn’t for lack of involvement by the owners.