Single gene that triggers macular degeneration is found

A variation in a single gene could be responsible for half of all cases of age-related macular degeneration, researchers said Thursday in a finding that could lead to better treatment for a leading cause of blindness. Three separate teams of scientists, reporting in the journal Science, all pinpointed a gene called CFH, for ''complement factor H." It is involved in a component of the immune system that regulates inflammation. ''This adds a major piece to the jigsaw puzzle in understanding age-related macular degeneration," said Stephen Daiger of the Human Genetics Center at the University of Texas Health Sciences Center in Houston. Age-related macular degeneration affects between 10 million and 15 million people in the United States alone and is the leading cause of blindness among the elderly. People who know they are at high risk can make sure they watch their diet -- eating fruits and vegetables lowers the risk-- and quit smoking, Daiger said.

REUTERS