The Royals' Kevin Appier, trying to come back from elbow surgery, left the game against Minnesota in the second inning. There was no immediate word on what might have been wrong.
Toronto's Josh Towers, who pitched for Baltimore in 2001 and 2002, has yielded 10 runs in two starts this season, both against the Orioles.
Detroit improved to 10-7. Last year, the Tigers didn't get their 10th win until May 22, when they were 10-35.
`President' Josiah Bartlet (Martin Sheen) threw out the first pitch at Camden Yards as a scene of the final episode of the "West Wing" was taped.
B.J. Surhoff went 3 for 3 for the Orioles and is 5 for 8 in his last two starts.
Oakland's Barry Zito, the 2002 Cy Young Award winner, allowed a career-high nine runs and 10 hits in four innings as his ERA ballooned from 3.32 to 6.26.
Athletics' Mark Kotsay has reached base to start the game in each of his last five games.
Seattle's Raul Ibanez sustained a bruised tailbone from a collision with Scott Spiezio as Spiezio made a catch in short left field in the sixth. Ibanez stayed in the game but was replaced by Quinton McCracken in the seventh.