With his two RBIs in the first, Orioles' Rafael Palmeiro passed Honus Wagner for 17th all-time with 1,733 career RBIs.
Tampa Bay's Carl Crawford stole two bases, pushing his major league-leading total to 37. He also became just the eighth player since 1900 to steal 100 bases before the age of 23.
The White Sox lead the Windy City series, 22-18, and have won the last four series against the Cubs. They won two of three games last weekend at US Cellular Field.
Pittsburgh's Oliver Perez leads NL starting pitchers with an average of 10.9 strikeouts per nine innings and has 348 strikeouts in 309 career innings.
Montreal's Livan Hernandez is tied with Anaheim's Bartolo Colon for most complete games since the start of the 2002 season (17).
Cubs' Aramis Ramirez left in the seventh with a strained right groin following a hard slide into third.