The Orioles avoided their first four-game sweep in Oakland since Aug. 23-26, 2004, jumping on Anderson (1-1) two days after the A’s gave the pitcher a $12.5 million, four-year contract.

Brian Matusz (2-0), like Anderson a hard-throwing lefty, delivered a much-needed morale boost for the struggling Orioles in his first career outing against Oakland. He struck out eight, allowing three runs on eight hits and one walk in 6 1/3 innings.

Baltimore (2-11) had lost nine in a row since its lone previous victory at Tampa Bay April 8, and is off to the franchise’s worst start since beginning 0-21 in 1988. The Orioles also ended a nine-game losing streak at the Coliseum dating to July 22, 2007.

Anderson, an 11-game winner in his rookie campaign of 2009, needed only 25 pitches to get through the first two innings. He retired the first eight batters of the game before giving up consecutive two-out singles to Cesar Izturis and Adam Jones and then Wigginton’s two-run double.

Yankees 5, Rangers 2 — Mark Teixeira hit his first home run of the season and Ramiro Pena delivered a key single while filling in for an ailing Derek Jeter as host New York completed a three-game sweep of Texas.

Andy Pettitte pitched four-hit ball for eight innings. The World Series champions won their fourth in a row, taking advantage of a wild Rich Harden to hand Texas its fourth straight loss.

Teixeira led off the third with a high-arching drive into the second deck in right field. He was hitting only .100 (4 for 40) this season when he connected. It was 2-2 with two outs and the bases loaded later in the third when Pena looped a soft, two-run single for his first hit of the season. He started because Jeter was ill with a cold.

Giants 1, Dodgers 0 — Manny Ramirez hit a two-run, pinch-hit home run in the eighth for career homer No. 548, lifting Los Angeles past San Francisco at Chavez Ravine.

Ramirez, who didn’t start for the second straight day because of tightness in his right calf, drove a 1-and-2 pitch from righthander Sergio Romo into the left-field pavilion with one out after Barry Zito walked pinch hitter Garret Anderson.

Angels 3, Blue Jays 1 — Ervin Santana came within one strike of a shutout as Los Angeles completed its first three-game sweep in Toronto since 2004.

Santana was dominant, setting down 17 in a row before Adam Lind homered to right on a 3-and-2 pitch with two outs in the ninth.

Indians 7, White Sox 4 — Shin-Soo Choo hit a grand slam and drove in five runs to lead Cleveland past visiting Chicago.

Choo went 2 for 3 with a walk, hitting his second career slam for a 7-0 lead in the second off Gavin Floyd. Fausto Carmona (2-0) gave up three runs over six innings as the Indians completed their first three-game home sweep of Chicago since May 2003.

Royals 10, Twins 5 — Alberto Callaspo had two home runs and a career-high six RBIs to propel Kansas City over host Minnesota.

Tigers 4, Mariners 2 — Max Scherzer pitched six solid innings and Miguel Cabrera hit a three-run homer into the second deck as Detroit doubled up host Seattle.

Brewers 11, Nationals 7 — Craig Counsell’s grand slam highlighted a 10-run first inning and Milwaukee held on to avoid a three-game sweep in Washington.

Jason Marquis (0-3, 20.52 ERA) was pulled before recording an out. He faced seven batters, and all reached: four singles, two hit batsmen, one walk. Miguel Batista served up Counsell’s first homer of the season.

Cardinals 5, Mets 3 — Adam Wainwright threw a four-hitter with nine strikeouts and scored on Ryan Ludwick’s tiebreaking two-run homer in the eighth as host St. Louis handed New York its fourth straight series loss to open the season.

Braves 4, Rockies 3 — Rookie Jason Heyward drove in two runs with a bases-loaded single with two outs in the ninth as host Atlanta rallied off Colorado closer Franklin Morales, who loaded the bases by giving up a single and two walks.

Astros 3, Cubs 2 — Pedro Feliz hit a go-ahead sacrifice fly in the 10th inning after Geoff Blum tied it with an RBI double in the ninth, and Houston rallied to defeat Chicago at Wrigley Field.

Pirates 5, Reds 3 — Paul Maholm pitched four-hit ball into the seventh inning and Jason Jaramillo had a three-run double as host Pittsburgh trimmed Cincinnati.

Marlins 2, Phillies 0 — Nate Robertson pitched into the seventh inning in outdueling Cole Hamels and Dan Uggla drove in both runs, leading visiting Florida to its second straight win over Philadelphia.

Padres 5, Diamondbacks 3 — Chase Headley hit a go-ahead, two-run double with two outs in the seventh and host San Diego rallied for five runs to beat Arizona.