Patterson, who tied a career high with five hits, led off the 14th with a drive to right off Gavin Floyd (5-5) for his third of the season. It was the fourth winning homer of his career.

Floyd started and went seven innings for Chicago in Wednesday’s loss at Texas. He came out of the bullpen in the 13th, his first relief appearance since Aug. 24, 2007, against the Red Sox.

Blue Jays lefthander Luis Perez (1-0) pitched 3 2/3 shutout innings for his first career win.

Brent Lillibridge homered for the White Sox.

Juan Rivera’s bases-loaded double in the seventh gave the Blue Jays an 8-6 lead, but their struggling bullpen couldn’t hold on.

The blown save was the third of the season for Frank Francisco, who has lost twice and has two blown saves in his past four games.

Twins 1, Angels 0 — Danny Valencia hit a bases-loaded single in the bottom of the 10th inning, lifting Minnesota over visiting Los Angeles after spot starter Anthony Swarzak held the Angels hitless into the eighth.

Swarzak, a late fill-in on the mound for Francisco Liriano, gave up a one-out double in the eighth to Peter Bourjos for the Angels’ first hit. Liriano was scratched the day before because of shoulder soreness.

Jered Weaver needed a season-high 128 pitches in nine innings, but he gave up only two hits and two walks, striking out seven.

The teams combined for only three hits until the decisive 10th, when Valencia lobbed a medium fly over Torii Hunter’s head in right field.

Indians 7, Rays 3 — Shelley Duncan and Orlando Cabrera each had two RBIs, Carlos Carrasco (4-2) pitched six solid innings, and Cleveland beat host Tampa Bay.

Rangers 10, Royals 1 — Mitch Moreland, Mike Napoli, and Endy Chavez hit consecutive homers to match a club record and back Matt Harrison’s five-hit shutout pitching over six innings as host Texas beat Kansas City.

Pirates 10, Cubs 0 — Paul Maholm (2-7) pitched a three-hitter and Ronny Cedeno, Lyle Overbay, Chris Snyder, and Andrew McCutchen each homered as Pittsburgh routed host Chicago.

Braves 7, Reds 6 — Chipper Jones’s single in the 12th inning drove in Jordan Schafer to give host Atlanta the win over Cincinnati.

Rockies 15, Cardinals 4 — Chris Iannetta homered twice and drove in a career-high six runs and Juan Nicasio pitched seven solid innings in his major league debut as scuffling Colorado routed St. Louis in Denver.

Brewers 3, Giants 2 — Pinch hitter Jonathan Lucroy’s bases-loaded suicide squeeze scored Ryan Braun with one out in the ninth, lifting host Milwaukee.

Diamondbacks 11, Astros 3 — Zach Duke (1-0) allowed three hits over seven innings and hit a three-run homer in his first game of the season as Arizona won in Houston.

Phillies 5, Mets 2 — Ryan Howard hit a tiebreaking double in the eighth inning and Cole Hamels (7-2) struck out a season-high 10 for visiting Philadelphia.

Padres 2, Nationals 1 — Tim Stauffer (1-3) pitched seven innings for his first win of the season, Blake Tekotte had the first two hits of his major league career, and San Diego won in Washington in a matchup of baseball’s weakest-hitting teams.

Athletics 4, Orioles 2 — Coco Crisp had two hits and drove in the go-ahead run to help host Oakland beat Baltimore.

Marlins 6, Dodgers 1 — Greg Dobbs went 3 for 5 and drove in two runs as Florida won in Los Angeles.