Reds send Astros to 7th straight loss with 4-1 win
Leake (2-5) had a season-high seven strikeouts in seven innings, yielding just one run and four hits. Aroldis Chapman struck out the side in the ninth for his fourth save.
Houston has dropped seven straight in its longest skid since it lost seven in a row last August.
Joey Votto hit a two-out single in the first and scored on Brandon Phillips' double off the wall in center, putting Cincinnati up 1-0. Bruce then singled in Phillips.
Houston starter J.A. Happ (4-5) allowed three runs and five hits in seven innings.