ANAHEIM, Calif. — It has been a season of unexpected and exciting victories for the Red Sox. But they took a stunning loss in the early hours of Sunday morning.
The Los Angeles Angels scored four runs in the ninth inning to tie the game then came away with a 9-7 victory in the 11th when Josh Hamilton hit a two-run walkoff home run.
It was the first time this season the Red Sox lost a game they led by four runs. Their five-game win streak was snapped.
Craig Breslow (2-2) allowed a one-out single by Brad Hawpe before Hamilton drove a slider out to center for his 12th home run.
Dane De La Rosa (4-1) pitched a perfect inning for the win. The last eight Red Sox went in order. The game lasted 4 hours 22 minutes.
The Red Sox took a 7-3 lead into the ninth inning and turned to rookie Alex Wilson for what looked to be mop-up duty. But the Angels scored four runs, all coming with two outs.
With two outs and a runner on first, Wilson allowed a single by J.B. Shuck then hit Mike Trout with a pitch. Red Sox manager John Farrell called in closer Koji Uehara for the fifth time in the last seven days.
He got two strikes on Albert Pujols before giving up a two-run single to center field.
Hamilton followed with an RBI single to right field, cutting the lead to 7-6.
When Howie Kendrick grounded to third base, the game should have been over. But Brandon Snyder, playing his seventh game for the Red Sox, threw the ball over Dustin Pedroia’s head at second base and the game was tied.
Uehara struck out Mark Trumbo swinging to end the inning. But it was his third blown save.
The Red Sox also suffered what looked to be a significant injury. Lefthanded reliever Andrew Miller left the game in the seventh inning after injuring left foot while going to back up home plate.
Miller could not put any weight on his foot and had to be helped off the field and into the clubhouse. The 28-year-old lefthander is having the best season of his career, posting a 2.64 earned run average over 37 appearances.
Miller has struck out 48 over 30⅔ innings and allowed 25 hits. He has been one of the team’s most effective setup men. His loss would leave Breslow as the only healthy lefthanded reliever on the roster.
The Sox had 12 hits off six Angels pitchers. Daniel Nava was 4 for 6 with two doubles, one RBI, and two runs. Jarrod Saltalamacchia was 2 for 4 with two doubles, two walks, and two RBIs.
Sox starter Ryan Dempster went 6⅓ innings. He allowed three runs (two earned) on seven hits. Dempster walked two and struck out four.
The righthander has a 3.33 earned run average in his last eight starts. He has gone at least six innings in seven of those starts.
The depleted Angels started righthander Jerome Williams on two days of rest. He faced the Cardinals on Wednesday and didn’t get through the second inning, giving up seven runs on four hits and four walks.
The Red Sox didn’t hit him quite that hard. But Williams was pulled before he could get an out in the fourth inning. He allowed five runs (four earned) on seven hits.
Jacoby Ellsbury started the game by extending his hit streak to 16 games with a single to center. David Ortiz then singled with two outs.
With Napoli at the plate, Ellsbury stole third and scored when the throw from catcher Chris Iannetta went into left field.
Nava singled to start the second inning and went to third when Saltalamacchia doubled to right field.
Brock Holt, in his first at-bat for the Red Sox after being called up earlier in the day from Triple A Pawtucket, drove the ball down the line in left for a sacrifice fly.
After the Angels went ahead with two in the second and another in the third, the first five Red Sox reached base in the fourth inning and three of them scored.
Mike Napoli walked and went to third on a double by Nava when left fielder Shuck was slow to retrieve what should have been a single.
Saltalamacchia’s double to left field scored two runs. Holt followed with a ground ball to first base. Pujols, usually sound defensively, skipped a throw to third base and Saltalamacchia was safe.
Jose Iglesias followed with an RBI single. Iglesias has reached base safely in 41 of 43 games in which he has had a plate appearance this season.
Reliever Garrett Richards got two outs before Pedroia walked to load the bases. Ortiz had a chance to break the game open but struck out swinging.
The lead grew to 6-2 in the sixth inning when Shane Victorino tripled to right field and scored on a single by Pedroia. It was the 24th triple of the season by the Sox, adding to their American League lead. They had 16 all last season.
Dempster had a rocky first three innings before settling in.
Up 2-0, he allowed two runs in the second inning. Kendrick started the inning with his second home run in as many nights, a line shot to center. With one out, Erick Aybar hit a slow grounder to the right side.
Dempster tried to flip the ball to first base and it flew over the head of Napoli. Aybar ended up on second base and scored on a single by Iannetta.
Trout gave the Angels a 3-2 lead in the third inning with a mammoth home run to left field that cleared both bullpens and landed halfway up the bleachers.
Dempster shut the Angels out in the four innings that followed. He got some defensive help from Victorino in the fifth inning.
Shuck led off with a groundball up the middle. What should have been a single turned into a double as Shuck challenged the arm of Ellsbury and beat the three-hop throw to second base.
Trout followed with a fly ball to right field. Shuck tried for third and Victorino threw him out. It was his sixth assist of the season.Peter Abraham can be reached at firstname.lastname@example.org.