David Ortiz hit his 53d home run, on a 3-and-2 pitch from Blue Jays lefty Gustavo Chacin, to give the Sox a 1-0 lead in the first. The home run was Ortiz's 32d on the road, which ties the AL record for home runs on the road set by Babe Ruth when he was with the Murderers' Row Yanks of 1927.