Here are the lineups:
RED SOX (64-40)
Pitching: LHP Jon Lester (10-4, 3.23)
WHITE SOX (52-52)
Pitching: RHP Philip Humber (8-6, 3.27)
Game time: 7:10 p.m.
TV/Radio: NESN / WEEI
Notes: The Red Sox have lost seven straight against the White Sox, their longest streak since losing eight straight against them in 1964. They have dropped 13 of 15 against their Chicago cousins. ... Lester is 2-3, 5.94 in six career starts against Chicago. He had a poor game against them on May 30, allowing seven runs on eight hits and four walks over 5.2 innings. ... Humber has faced the Red Sox once in his career, that coming on May 31. He allowed four runs on nine hits over 7.2 innings with one walk and five strikeouts. ... Saltalamacchia has a career-best seven-game hit streak going. He is 10 for 29 with three homers and eight RBIs in the streak. ... Reddick is 7 of his last 31 (.226) with three RBIs.
Stat of the Day: Gonzalez may have led the American League to the Home Run Derby title. But he hasn't hit one for the Red Sox since July 7. He has gone 69 at-bats without a homer, the longest drought on the team.
Song of the Day: "Chicago Seemed Tired Last Night" by The Hold Steady.