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Tonight's Red Sox Lineup: Dustin Pedroia's Back and Leading Off

Dustin Pedroia is back in the lineup and batting leadoff for the Red Sox tonight in Chicago. The Red Sox second baseman had a cortisone shot Monday for a sore left wrist and came into Tuesday night's game to pinch run for Mike Napoli. Pedroia's been out of the starting lineup with the wrist issue since Saturday.

Pedroia is 16-for-48 (.327) with three walks and four strikeouts when batting from the leadoff position from 2011-13. Pedroia has yet to draw a walk this season in 55 at-bats.

"The thought has been when he went through that stretch, the week prior to the wrist injury bothering him, and I think there were times when the leadoff guy did not get on, he looked to do a little bit more in terms of trying to drive the ball for extra base hits," Farrell said on WEEI's "Dale and Holley Show" Wednesday afternoon. "What we're trying to do is just to get him to to think about seeing pitches, which when he's right he does so well, just to get on base, and let guys behind him start to build the inning on top of his on-base so it's a matter of taking away the thought of trying to do more than maybe right now anyone is capable of and just see pitches and give some sense to the guys behind him watching how the opposition might look to attack some people, and just give us the ability to get an inning started."

We'll have the rest of the lineups for the second game of the Red Sox-White Sox series that gets underway at 8:10 p.m when they are announced.

RED SOX (5-9)
1. Dustin Pedroia (R) 2B
2. Xander Bogaerts (R) SS
3. David Ortiz (L) DH
4. Jonny Gomes (R) RF
5. Grady Sizemore (L) LF
6. A.J. Pierzynski (L) C
7. Daniel Nava (S) 1B
8. Ryan Roberts (R) 3B
9. Jackie Bradley Jr. (L) CF
SP: Clay Buchholz (R) (0-1, 6.97 ERA)

WHITE SOX (8-6)
1. Adam Eaton (L) CF
2. Marcus Semien (R) 2B
3. Conor Gillaspie (L) 3B
4. Jose Abreu (R) 1B
5. Adam Dunn (L) DH
6. Dayan Viciedo (R) RF
7. Alejandro De Aza (L) LF
8. Alexei Ramirez (R) SS
9. Adrian Nieto (S) C
SP: John Danks (L) (1-0, 4.15 ERA)

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Game time: 8:10 p.m.

Location: U.S. Cellular Field, Chicago

TV/Radio: NESN / WEEI (93.7 FM)

Notes: John Farrell on WEEI's "Dale and Holley Show" said Mike Napoli remains day-to-day after dislocating his left ring finger sliding into second base in last night's loss. Farrell said Napoli has no fracture or ligament issues with the injured finger but he will not play in Wednesday night's game as the swelling subsides. Closer Koji Uehara planned to throw in the bullpen Wednesday, making progress after suffering a sore right shoulder... Clay Buchholz looks for his first win and to stop the bleeding in Game 2. Buchholz improved on his first start with a solid six innings in New York last week. ...The Red Sox have lost a season-high three straight games for the second time this year... Last year’s Red Sox team was the first that did not endure a losing streak of more than three games since the 1903 club did it in a 138-game schedule... Of Boston’s nine losses this season, four have been decided by one run...That mark matches the Royals for the most one-run losses among AL teams this season.

David Ortiz on the Boston Marathon from this week's Sports Illustrated: "I love the Marathon," Ortiz said to SI. "There's no chance in hell I could run such a long distance -- I can barely run the bases anymore -- so I have great respect for those runners. In past years I always walked down near the finish line to watch when our game at Fenway was over, to cheer on the runners with my family. I'll be there this year for sure. Maybe I'll try to take selfies with as many people as I can while I'm there -- that will be my marathon. That's the great thing about this race, and this city and this country. No matter what happens, what anyone tries to do to us, we will always find a way to stay strong."

Steve Silva can be reached at ssilva@boston.com. Follow him on Twitter @stevesilva