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Game 45 Lineups: After Losing Five Straight, Red Sox Mix it Up

After losing a fifth straight game -- and after never getting closer than three despite having the tying run at the plate with nobody out in three of the final four innings -- Red Sox manager John Farrell decided to jumble his lineup as his team takes on the Blue Jays at Fenway Park. In fact, only David Ortiz will hit Wednesday out of the same slot where he'd hit on Tuesday. Here are the details:

RED SOX (20-24)
1. Grady Sizemore (L) CF
2. Dustin Pedroia (R) 2B
3. David Ortiz (L) DH
4. Jonny Gomes (R) LF
5. A.J. Pierzynski (L) C
6. Shane Victorino (S) RF
7. Mike Carp (L) 1B
8. Xander Bogaerts (R) SS
9. Brock Holt (L) 3B
SP: Clay Buchholz (RHP) (2-3, 6.17 ERA)

BLUE JAYS (24-22)
1. Jose Reyes (S) SS
2. Melky Cabrera (S) LF
3. Jose Bautista (R) RF
4. Adam Lind (L) DH
5. Edwin Encarnacion (R) 1B
6. Juan Francisco (L) DH
7. Brett Lawrie (R) 3B
8. Dioner Navarro (S) C
9. Anthony Gose (L) CF
SP Drew Hutchison (RHP) (2-3, 3.64 ERA)

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Game time: 7:10 p.m.

Location: Fenway Park, Boston

TV/Radio: NESN / WEEI (93.7 FM) / WCEC (1490 AM Spanish)

Notes: With the Red Sox an AL-worst 10-19 against righty starters this season, this lineup features eight of the team's nine best bats against RHPs (per OPS) thus far. Mike Napoli, the club's second best, sits ... This will be the first game since Sizemore filled the role on April 23 that the Sox leadoff hitter will be someone other than Pedroia ... Sizemore is batting .103 (4-for-39) with a .146 OBP batting out of the leadoff spot this season ... Victorino had batted second in his first 18 games of the season, though he is batting .232 with a .289 OBP against right-handers ... This is the second time this season Gomes has batted clean-up ... After starting 22 consecutive games in center field, Jackie Bradley Jr. sits for the second time in four contests.