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Lackey on the Hill for Red Sox' First Game at Safeco Field in 2014

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John Lackey had perhaps the best start of his Red Sox career his last time out, going nine innings against the Twins and allowing no runs on three hits with one walk and nine strikeouts. Jim Davis/Globe Staff

The Red Sox snapped their three-game skid on Sunday, outlasting the Oakland A’s despite Koji Uehara blowing a two-run lead in the ninth.

The Sox now head to Seattle for three games to end the West Coast portion of their 10-game road trip.

John Lackey, who has arguably been the ace of the Red Sox pitching staff this season, gets the start on Monday. Lackey is 8-2 in 15 starts this year with a 2.96 ERA; he went nine innings in his last outing, shutting out the Minnesota Twins on June 18 on just three hits and one walk with nine strikeouts.

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Lackey has a great deal of experience against the Mariners due to his eight seasons with the Los Angeles Angels, starting 31 games and holding a 15-10 record with a 3.61 ERA. He faced them once in 2013, throwing eight innings on July 31 and allowing three runs on eight hits with a walk and six strikeouts; he was not factored into the decision of a 5-4 Red Sox win.

Robinson Cano has far and away faced Lackey the most of any Mariners hitter, going 18-for-66 with three walks. Other in Seattle’s lineup who have double digit plate appearances against Lackey include Willie Bloomquist, who is 5-for-15; Endy Chavez, 8-for 13 with a sac fly; and Dustin Ackley, 4-for-9 with a walk.

The Mariners will be throwing out the unquestioned ace of their staff, four-time All-Star and 2010 AL Cy Young Award winner Felix Hernandez. Hernandez has been very good for Seattle this year, going 8-2 in 16 starts with a 2.22 ERA.

Hernandez has made 14 career starts against the Red Sox, going 7-2 with a 3.00 ERA. He last faced them on Aug. 1 of last season, giving up one run on six hits with two walks and eight strikeouts.

Mike Napoli and A.J. Pierzynski, former AL West players, have each faced Hernandez 42 times, with Napoli going 6-for-36 with six walks and Pierzynski going 9-for-40 with two walks. Dustin Pedroia is 10-for-37 with four walks against Hernandez; David Ortiz is 10-for-31 with six walks; Jonny Gomes is 3-for-14 with two walks; and Daniel Nava is 3-for-14.