Rachel Ramsey had a goal and two assists for Minnesota, which capped a perfect season at 41-0.
It was Boston University's second appearance in the national championship in the last three seasons – the Terriers lost the 2011 title game to Wisconsin. Minnesota, which defeated Boston College in the semifinals, also won the title in 2012, 2005, and 2004.
Mira Jalosuo gave Minnesota a 1-0 lead 11:38 into the first period and Hannah Brandt made it 2-0 with a short-handed goal at the 18:32 mark.
Sarah Lefort put BU on the board just 16 seconds later with a power play goal that made it 2-1.
In the second period, Amanda Kessel and Milica McMillen scored to increase Minnesota's lead to 4-1.
Marie-Philip Poulin and Jenelle Kohanchuk had third-period goals for Boston University (28-6-3).
- Michael Vega
- Mark Blaudschun
- Nancy Marrapese-Burrell