Mississippi at No. 1 Alabama
The Crimson Tide (4-0), who are allowing just 5.2 points per game, welcome a 3-1 Rebels squad that has already surpassed its win total from last season.
No. 2 Oregon at Washington State
For once it was the Ducks’ defense that made headlines last week, posting its first conference shutout in nine seasons by blanking then-No. 22 Arizona. The game will be at CenturyLink Field, home of the Seattle Seahawks.
Towson at No. 3 LSU
The Tigers (4-0), who survived a scare last weekend at Auburn, have shown a lack of discipline, averaging eight penalties per game this season.
No. 4 Florida at South Florida
The Seminoles (4-0), second in the nation in scoring (56.2), hit the road for the first time this season. The Bulls (2-2) have lost two straight.
Tennessee at No. 5 Georgia
A matchup of the SEC’s top two offenses: Georgia is averaging 530 yards per game, Tennessee 513.7. The Bulldogs (4-0) have scored at least 40 points in all four games. The Volunteers (3-1) have lost eight straight at Georgia.
No. 6 South Kentucky at Kentucky
The Gamecocks (4-0) are on an eight-game winning streak dating to last season. The Wildcats (2-2) are allowing 400.2 yards and 29 points per game.
No. 9 West Virginia vs. No. 25 Baylor
The Mountaineers (3-0) have waited a long time for their Big 12 debut. It should be a shootout as Baylor ranks fifth in the nation in scoring (51.3) and West Virginia 10th (47.3).
No. 12 Texas at Oklahoma State
Texas sophomore quarterback David Ash (seven TD passes, zero interceptions) will need to keep up with a Cowboys team that leads the nation in total yardage (686.7) and scoring (62.3).
No. 14 Ohio State at No. 20 Michigan State
The 3-1 Spartans, with the top defense in the Big Ten (233.5 yards, 11.7 points per game) will get a test against Buckeyes QB Braxton Miller (seven TDs passing, seven TDs rushing). Ohio State (4-0) is averaging 37.5 points per game.
No. 15 TCU at SMU
The Mustangs (1-2) were the last team to defeat the Horned Frogs (3-0), who boast the nation’s longest winning streak at 11 games.
No. 17 Clemson at Boston College
The Eagles (1-2) are coming off a bye. The Tigers (3-1) are coming off a 49-37 loss to Florida State in which they allowed 667 yards.
No. 18 Oregon State at Arizona
Rich Rodriguez and the Wildcats (3-1) were embarrassed last weekend by Oregon, 49-0. They need to bounce back against a Beavers team that’s already notched two wins over ranked opponents.
No. 19 Louisville at Southern Miss
The Cardinals (4-0) have won their last two games by a combined 12 points. Southern Miss (0-3) has been a mess this season, allowing 38.3 points a game while scoring just 17 per.
Wisconsin at No. 22 Nebraska
The Badgers (3-1) could be without running back Montee Ball, who suffered his second head injury in less than two months last weekend. The Cornhuskers (3-1) are averaging 48.5 points per game this season.
No. 24 Boise State at New Mexico
The Broncos (2-1) have failed to score more than one touchdown in two of their three games. New Mexico is giving up 32.2 points per contest.