Montel Harris is the leading rusher in Boston College history. The senior from Jacksonville, Fla., rushed 22 times for 108 yards in yesterday’s 27-19 loss to Wake Forest, breaking Derrick Knight’s school record.

Harris set the mark with a 26-yard fourth-quarter run that set up BC’s only touchdown, and now has 3,734 career rushing yards. But in a loss, it left a bittersweet taste in Harris’s mouth.

“In the moment, breaking the record is second on my list,’’ he said. “We work hard to get a win and we came up short this time. I’m sure I’ll look back at the end of the season and view this as a huge accomplishment. Right now, I’m trying to help our team get this season going in the right direction with some wins.’’

Harris said he had talked to Knight about the record. “I met him for the first time the other day in the training room,’’ said Harris. “He asked me if I was ready to break the record. I told him, ‘Yes, I’m ready.’ ’’

Range finder Sophomore Nate Freese kicked four field goals, including a career-best 52-yarder. “It did feel good to hit that,’’ he said. “But at the same time, they are all worth 3 points, so no one is more important than the other. But it definitely did feel good to connect on a long one.’’ . . . The Eagles’ defense again had too many holes, allowing 392 yards . . . Wake Forest won for the first time in the last five meetings . . . BC linebacker Luke Kuechly had 14 tackles, his nation-best 27th straight game in double digits . . . Colin Larmond Jr. caught five passes for 80 yards . . . Running back Andre Williams went down with a sprained right ankle . . . Linebacker Kevin Pierre-Louis had 10 tackles, his third time this season with 10 or more . . . Freshman defensive back Al Louis-Jean had his first career interception.

Mark Blaudschun can be reached at blaudschun@globe.com.