The Hoyas (15-3, 5-2 Big East) outrebounded DePaul 47-25 and consistently worked inside for second shots. Henry Sims added 16 points and Otto Porter had 15 rebounds for Georgetown.

Clark made 11 of 14 shots from the field, including 5 of 7 from behind the 3-point line.

Cleveland Melvin scored 19 points and Moses Morgan had 17, including five 3-pointers, for the Blue Demons (10-8, 1-5), who lost their fourth straight.

Clark's dunk on a break with 6:29 left gave the Hoyas a 14-point lead, but DePaul kept scrapping on defense and cut it to seven on a jumper by Morgan with 2:44 left. But Clark made two free throws and Jabril Trawick had a three-point play for the Hoyas.

Clark, who had 13 points in the first half, connected on his third 3 in a quick 7-0 run as Georgetown went up by 11 points late in the half.

But DePaul's Brandon Young dribbled for about 5 seconds and then hit a long 3-pointer at the buzzer to sliced the lead to 37-31.

DePaul scored the first five points of the second half, but just as the Blue Demons were about to gain the momentum, Clark responded with another 3-pointer and Sims scored consecutive baskets after grabbing offensive rebounds. After a timeout, Clark made a steal and drove in for another basket to cap a 9-0 run and put the lead back to 10.

Morgan found the range on two 3-pointers and Melvin had a jumper in an 8-0 run by the Blue Demons that made it a two-point game with 14 minutes to go.

Once again the Hoyas' strong rebounding and Clark stopped the run. Clark had a driving reverse layup, Hollis Thompson scored on a follow to build it back to eight and Clark made another 3-pointer in a 12-2 run for a 60-48 lead.

The Hoyas played without guard Markel Starks, who came down with a stomach ailment and was not able to go. He had started the Hoyas' first 17 games.

The Hoyas have won 11 straight against DePaul and lead the series 20-6