49ers downgrade Manningham to out

San Francisco has announced that WR Mario Manningham has been downgraded to out for Sunday night’s game against the Patriots.

The 49ers had listed Manningham has doubtful in Friday’s report.

It will be the second consecutive game that Manningham will miss because of the right shoulder injury.

49ers beat reporter Matt Maiocco of CSN Bay Area said Manningham’s absence will mean more opportunities for Randy Moss to play in two-receiver sets.

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