Kaepernick took over as Smith went to the bench to be examined by medical personnel and soon left for the locker room.
One wild play late in the first half summed up this wacky day. Punter Hekker completed a 21-yard pass to safety Rodney McLeod from the end zone after Chris Culliver didn’t cover McLeod. Hekker did it again in the fourth quarter and had a notable 118.8 passer rating on the day.
On the Rams’ 14-play, 18-yard drive over the final minutes of regulation, Hekker faked an end-around and threw a 19-yard completion to Kendricks on fourth-and-8 from the Rams 33.
But the Rams’ defense couldn’t get a stop, allowing Kaepernick to get his team back into field-goal range for Akers to tie it.
The Rams played without a pair of starters held out for an unspecified team rules violation, cornerback Janoris Jenkins and wide receiver Chris Givens — and Fisher said afterward he isn’t sure if they will play next week at home against the New York Jets.
The 49ers will regroup to face the Bears in prime time.
‘‘It feels weird,’’ safety Donte Whitner said. ‘‘We’re about wins around here.’’
Notes: Rams LT Wayne Hunter played after missing two games with a back injury. ... Fans spelled out ‘‘THANK YOU VETERANS’’ in the stands with shiny red, white and blue cards after the first quarter. A special military coin also was used for the pregame toss on Veteran’s Day.
Online: http://pro32.ap.org/poll and http://twitter.com/AP_NFL