HOUSTON (AP) — Andre Johnson caught a screen pass from Matt Schaub and ran 48 yards for the winning touchdown in overtime as the Houston Texans rallied to beat Jacksonville 43-37 on Sunday.

Schaub threw a career-high five touchdown passes, completed a franchise-record 43 passes and finished with 527 yards passing, second most in NFL history. Warren Moon also threw for 527 yards for the Houston Oilers in December 1990 against Kansas City.

Norm Van Brocklin holds the record with 554 for the Rams in 1951.

Johnson caught 14 passes for 273 yards, both career highs. The Texans (9-1) won an overtime game for the first time at Reliant Stadium.

Chad Henne threw a career-high four touchdown passes in relief of injured Blaine Gabbert for the Jaguars (1-9). Rookie Justin Blackmon had 236 yards receiving.

FALCONS 23, CARDINALS 19

ATLANTA (AP) — Matt Ryan overcame a career-worst five interceptions, guiding Atlanta to its only offensive touchdown in the fourth quarter in a sloppy win.

The Falcons (9-1) turned it over a total of six times, but Michael Turner scored on a 1-yard run with 6:40 remaining to give Atlanta its first lead of the game. Ryan set up the score with four completions for 64 yards, including a 9-yarder to Tony Gonzalez on third-and-5 at the Arizona 10.

Coming off a bye, Arizona (4-6) lost its sixth straight game. The Cardinals tried to bolster their anemic offense by switching quarterbacks, replacing John Skelton with rookie Ryan Lindley, but Larry Fitzgerald couldn’t hang on to a fourth-down pass after Ryan’s fifth pick.

PACKERS 24, LIONS 20

DETROIT (AP) — Aaron Rodgers threw two touchdown passes, including a 22-yarder to Randall Cobb with 1:55 left to lift Green Bay.

Mason Crosby made a 39-yard field goal with 19 seconds to go after missing two field goals earlier in the game.

Matthew Stafford couldn’t put the Lions ahead on either of their last two drives in a game he'd like to forget.

Stafford threw two interceptions — one of which was returned 72 yards by Green Bay safety M.D. Jennings for a go-ahead score in the third quarter — and lost a fumble.

Green Bay (7-3) has won five straight and Detroit (4-6) has dropped two in a row.

COWBOYS 23, BROWNS 20 OT

ARLINGTON, Texas (AP) — Dan Bailey kicked a 38-yard field goal in overtime and Dallas overcame a critical fumble by Tony Romo that sparked a wild ending.

Bailey’s winning kick with 6:07 remaining in OT came after both teams punted once in the first overtime game at Cowboys Stadium. Bailey hit a tying 32-yard field goal with 2 seconds left in regulation.

Dallas (5-5) rallied from a 13-0 halftime deficit and went ahead 17-13 on Romo’s 28-yard pass to Dez Bryant.

A fumble by Browns rookie Brandon Weeden on a sack appeared to put the Cowboys in control, but Romo gave it right back with a fumble on another sack.

The Cowboys made one goal-line stand in the final minutes, but the Browns got another chance and went ahead 20-17 on Weeden’s 17-yard pass to Benjamin Watson.

BUCCANEERS 27, PANTHERS 21 OT

CHARLOTTE, N.C. (AP) — Josh Freeman threw a 15-yard touchdown pass to Dallas Clark in overtime to cap a comeback.

It was Freeman’s third touchdown pass of the game for the Buccaneers (6-4).

Carolina appeared to have the game in hand after a 29-yard touchdown pass from Cam Newton to Brandon LaFell put the Panthers (2-8) up 21-10 with 4:34 left in the game. But after a 40-yard field goal by Connor Barth, the Panthers were forced to punt, and Freeman led the Bucs 80 yards on seven plays in 50 seconds with no timeouts.

He finished the drive with a 24-yard touchdown pass to Vincent Jackson between three defenders with 12 seconds left. Freeman went back to Jackson for a 2-point conversion on a slant route to send the game into overtime.

PATRIOTS 59, COLTS 24

FOXBOROUGH, Mass. (AP) — The Patriots used three scoring passes from Tom Brady, two touchdowns on interception returns and another on a punt return to match a team single-game scoring record.

he first matchup between three-time Super Bowl winner Brady and star rookie Andrew Luck was no match.

The Patriots (7-3) won their fourth straight game and extended their lead in the AFC East to three games. The Colts (6-4) had their four-game winning streak stopped by the NFL’s best offense and one of its worst defenses.

This win was the Patriots’ most complete in a season in which they've averaged 35.8 points per game and lost their three games by a combined margin of four points.