Brees completed 12 of his first 13 passes and finished 26 of 39 for 307 yards. J osh Freeman endured one of his worst outings of the season for the Bucs (6-8), throwing four interceptions and losing a fumble.
Seahawks 50, Bills 17
Buffalo’s annual game in Toronto was all about Seattle. Rookie quarterback Russell Wilson ran for three touchdowns and threw for another — all in the first half — and the Seahawks (9-5) forced the Bills (5-9) into three straight turnovers to start the second half.
In winning for the fifth time in six games, Seattle inched closer to clinching a playoff berth. The Seahawks became the third NFL team to score 50 points in consecutive weeks, joining the Los Angeles Rams and New York Giants, both in 1950, according to STATS. The Bills dropped to 1-4 in regular-season games at Toronto since the series began in 2008.
Vikings 36, Rams 22
Adrian Peterson had an 82-yard touchdown run while piling up a season-best 212 yards on 24 carries, and Minnesota (8-6) scored 10 of its 23 points in the second quarter off turnovers by host St. Louis (6-7-1). That included a 29-yard interception return by defensive end Everson Griffen that staked the Vikings to a 24-7 lead.
Less than a year removed from a serious knee injury, Peterson has a career-best 1,812 yards rushing, leaving him 294 shy of breaking the season mark of 2,105 set by Eric Dickerson of the Los Angeles Rams in 1984 with two games left.
Cardinals 38, Lions 10
Host Arizona snapped its nine-game skid while sending Detroit to its sixth consecutive loss. The Cardinals (5-9) turned four turnovers by the Lions (4-10) into touchdowns, including Greg Toler’s 102-yard interception return.
Panthers 31, Chargers 7
Mike Tolbert rushed for two scores against his former team, and visiting Carolina (5-9) won consecutive games for the first time since last December. San Diego (5-9) clinched its first losing season since 2003. The Chargers were outgained, 372 yards to 164.
Raiders 15, Chiefs 0
Sebastian Janikowski kicked five field goals, Darren McFadden rushed for 110 yards, and host Oakland shut out Kansas City for just the second time in 107 matchups. The Raiders (4-10) snapped a six-game skid, while the Chiefs (2-12) lost for the 10th time in 11 games and stayed in the running for the No. 1 draft pick.