New England's linebackers vs. Buffalo's runners: The Bills have had success running this year no matter who carries the ball. Fred Jackson injured his knee in the season opener, but backup C.J. Spiller had two 100-yard games before getting injured in Week 3. Third-stringer Tashard Choice ran for 91 yards on 20 carries after Spiller left. The Patriots have been able to limit rushing attacks, allowing 243 total yards this season (seventh in NFL). Linebacker Jerod Mayo leads the team in tackles, and he could be instrumental in stopping the Bills' three backs.