16: Patriots vs. Steelers
Date: Sunday, Nov. 3, at 4:25 p.m. ET
Compelling story line: The Patriots and Steelers have been considered bitter rivals for a while, even though they are not divisional foes. Both teams have been near the top of the AFC for years. In fact, the Patriots (.760) and Steelers (.659) are two of the three winningest NFL franchises of the past 12 years.
The battle of the quarterbacks is underrated, and although Tom Brady has dominated the Steelers defense in recent years, Pittsburgh defensive coordinator Dick LeBeau was able to get Brady off his game in the last meeting (5.7 yards per pass attempt).
Interesting stat: The Steelers defense has dealt with some moving parts over the years, but they still held opponents to a 79 passer rating in 2012 (eighth-lowest in the NFL).
Bold prediction: The Steelers will not log a sack of Tom Brady in this contest.