13: Bills vs. Dolphins
Dates: Sunday, Oct. 20, at 1 p.m. ET and Sunday, Dec. 22 at 1 p.m. ET
Compelling story line: The Dolphins were in contention for a playoff spot at times in 2012, but their midseason loss to the Bills was one of several nails in their coffin. The Bills fell to the Dolphins later in the season, but the damage had already been done.
Things have changed since the last meeting, though, with new coaches and a new quarterback for the Bills. New defensive coordinator Mike Pettine will surely have something in store for Ryan Tannehill, and with questions about the Dolphins' fortitude on the offensive line, they will be under close watch as the Bills cook up a pressure-based game plan.
Interesting stat: C.J. Spiller picked up 303 yards from scrimmage in two games against the Dolphins in 2012.
Bold prediction: Ryan Tannehill will be sacked five times in one of his two meetings with the Bills defense.