Jones injured his left ankle on a goal-line play against the Texans a week earlier, but practiced all week and was listed as probable by the Patriots. Despite that designation, it is believed that Jones' participation was a game time/coaching decision.
Fellow rookie Justin Francis started at defensive end in Jones' place.
It was the second sprained ankle for Jones - he injured his right ankle against the Colts in November and missed two games.
The rookie told reporters on Monday that he will remain in the Foxborough area to rehab both sprains and will consult with the team on whether he will need surgery to repair either one.