Peyton Manning and the Patriots
Nov. 7, 2005: Colts 40, Patriots 21
The Colts entered the Week 9 matchup 8-0 and the Patriots were 4-3. Colts QB Peyton Manning was 0-7 against New England, and seemed to take the game personally, throwing for 321 yards, three touchdowns and one interception.
The other elements of the Colts's offense made great contributions as well: Edgerrin James ran for 104 yards and Marvin Harrison and Reggie Wayne (87) each caught nine passes for 128 and 124 yards, respectively.