Wie, who finished 12 under for the tournament, earned the winner’s check of $337,500 in the $2.25-million event at the St. Charles Country Club in Winnipeg, Manitoba.

Wie had five birdies, including on the 13th, 14th, and 15th holes. “I made a lot of crucial putts,’’ said Wie.

Jiyai Shin shot a 73 and tied for second with Kristy McPherson (66), defending champion Suzann Pettersen (69), and Jee Lee Young (69).

Wie led wire-to-wire after an opening 65 and was tied with Shin for the lead entering the final round at 10 under.

Ai Miyazato (69) of Japan, the No. 1-ranked player heading into the tournament, finished tied for 15th, while No. 2 Cristie Kerr (69) tied for eighth.

After Wie, 20, ended her round on the 18th green, her longtime friend Christina Kim sprayed her with champagne.

“I was trying to run away from her,’’ Wie said with a laugh. “All I was thinking in my mind was, ‘I’m wearing white pants, please be nice Tina.’ ’’

Wie said she’s heading back to school at Stanford after the LPGA’s next event — the P&G NW Arkansas Championship beginning Sept. 10.

European — Edoardo Molinari birdied the final three holes at Gleneagles in Scotland to win the Johnnie Walker Championship and secure a place on Europe’s Ryder Cup team.

The 29-year-old Italian received a wild-card pick from captain Colin Montgomerie, a few hours after shooting a 1-under 71 to beat Brett Rumford by a shot.

Molinari finished at 10-under 278. Overnight leader Francesco Molinari — Edoardo’s brother — shot 75 to share third with Jamie Donaldson and Miguel Angel Jimenez.

Champions — Bernhard Langer closed with a final-round 3-under 69 to win the Boeing Classic at Snoqualmie, Wash., his fifth tour victory of the season.