James Neal scored twice and Sidney Crosby had a goal and two assists to help the Pittsburgh Penguins beat Ottawa, 4-2, on Wednesday night in Pittsburgh in a game marred by the loss of Senators star defenseman Erik Karlsson to a left Achilles’ injury.

The Norris Trophy winner last season as the NHL’s top defenseman, Karlsson was cut by Penguins forward Matt Cooke’s skate blade as the two tangled along the boards late in the second period. The Senators said Karlsson will need surgery.

Pascal Dupuis also scored for Pittsburgh, Paul Martin had two assists, and Marc-Andre Fleury made 27 saves.

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Blues 4, Red Wings 3 — Alexander Steen stuffed in a rebound 52 seconds into overtime, lifting St. Louis to a slump-stopping victory over host Detroit.

St. Louis snapped a five-game losing streak that followed a 6-1 start.

St. Louis goaltender Jake Allen, making his first NHL start in his second game in the league, made 15 saves.

Flames 7, Stars 4 — Mike Cammalleri had three goals and an assist in his return from a hip injury to help host Calgary blast Dallas.

After missing the last three games because of a hip flexor, Cammalleri scored his first three goals of the season to reach 200 for his career.

Roman Czervenka added a goal and an assist, and Jay Bouwmeester and Jiri Hudler also scored. Alex Tanguay, Lee Stempniak, and Jarome Iginla each had two assists.