Joe Pavelski and Brad Winchester also had goals for the Sharks, who won for the third time in four games and extended their winning streak over the Red Wings to five, dating to last November.
Niklas Kronwall and Danny Cleary scored for the Red Wings, who have lost two straight since a four-game winning streak. Detroit has been beaten in five consecutive road games. Defenseman Brendan Smith made his long-awaited debut, but was never a factor.
Antti Niemi stopped 40 shots in the win. Jimmy Howard allowed four goals on 21 shots before being replaced by Ty Conklin, who allowed a goal on seven shots.