By Anthony Gulizia and Jason Mastrodonato, Globe Correspondents

After all the Thanksgiving madness, the playoffs are finally here.

If next year’s new statewide playoff proposal sticks after the two-year pilot run, this is the last time teams will square off in the Tuesday night semifinal games that will determine the playoff contenders.

Here’s a look at Tuesday’s 16 matchups, along with our playoff predictions.

Thanksgiving results: Anthony 4-6, Mastro 4-6
Season: Mastro 67-33, Anthony 63-37.

Division 1
No. 4 St. John’s Prep (9-1) vs. No. 10 Andover (10-1), Cawley Stadium in Lowell, 7:45:
Anthony: The cliché line says ‘Defense wins championships,’ and St. John’s Prep fits the bill. The Eagles give up just 9.1 points per game, and shut out Xaverian 9-0 on Thanksgiving to win the Catholic Conference title. St. John’s Prep 21, Andover 15.
Mastro: Xaverian’s Austin DeCarr isn’t a bad quarterback, but St. John’s Prep defense did its best to make him look like one on Thanksgiving. Yes, the Eagles can run the ball. Yes, Jack Sharrio can pass it when he needs to. Yes, their defensive line is as good as it gets. I don’t see a flaw in this team. St. John’s Prep 28, Andover 14.

No. 11 Brockton(8-3) at Weymouth (8-3), 7:45:
Anthony: Weymouth has plenty of speed in David Harrison and Ozzy Colarusso to keep this one close, but Brockton is hungry after missing out last year’s playoffs. It has proven so by winning five straight to end the season, and it will get back to the big game. Brockton 28, Weymouth 21.
Mastro: The way Austin Roberts has been playing, Brockton doesn’t look beatable right now. Brockton 27, Weymouth 14.

Division 1A
No. 16 Masconomet (9-2) vs. No. 2 Everett (9-1) at Manning Field in Lynn, 7:45:
Anthony: Everett was banged up most of the season, and the Tide hasn’t played a game since Nov. 9, so they’ve had plenty of time to heal. Any chance they come out flat after the layoff? Maybe. But don’t expect it from John DiBiaso’s crew. Everett 27, Masconomet 15.
Mastro: I do wonder what the long layoff will do for Everett, which hasn’t played since Nov. 9, but the good news for DiBiaso is that his team is finally healthy, and I think that’s going to be the difference. But I’m really not discounting Masco in this game. They have a great offensive line, too, and I think they might be able to put up enough points to stay close. I predict a great game. Everett 21, Masco 14.

No. 12 Lincoln-Sudbury (10-1) vs. No. 1 Barnstable (10-0), at Taunton, 5:15:
Anthony: What would the 1A Super Bowl at Gillette be without an Everett-Barnstable rematch? The Crimson Tide is dying for a second shot at Barnstable, and here’s to hoping they get it because it’s sure to be an even better battle the second time around. Did I mention that Nick Peabody is pretty good? Barnstable 31, Lincoln-Sudbury 20.
Mastro: I’ve seen Barnstable in two very close games this year, and I’m beginning to think their defense is really underrated. The Red Raiders sure can throw the ball, and that usually leads the news. But against both Everett and Bridgewater-Raynham, Barnstable came up with defensive stops late in the game. If this is close, I’m giving Barnstable’s defense the edge. Barnstable 22, Lincoln-Sudbury 16.

Division 2
Tewksbury (7-4) at No. 5 Reading (11-0), 7:45:
Anthony: Last year, Tewksbury got the best of the Middlesex champs. This year, it’ll be a bit more difficult. Reading gives up just 4.7 points per game, and quarterback Drew Belcher can score just as easily as his team can keep opponents off the board. Reading 20, Tewksbury 7.
Mastro: There aren’t any Tewksbury names that stand out when you look at the leaderboard, but this is a team that’s been in every game this year – and that’s a tough schedule the Redmen had to get through. They’ve played close in shootouts (51-42 loss to Andover, 49-42 win over North Andover) and in defensive stalemates (16-7 loss to Central Catholic, 15-12 loss to Lincoln-Sudbury). Something about this team screams upset to me. Tewksbury 21, Reading 13.

No. 3 Duxbury (11-0) vs. Mansfield (7-4), at Bridgewater-Raynham, 7:45:
Anthony: Duxbury linebacker Marshall McCarthy is a force to be reckoned with, and the Dragons' offense gets plenty of time behind 6-foot-6 lineman Rob Kosharek. Duxbury has won 37 straight contests – there’s no question they know how to win. Duxbury 21, Mansfield 14.
Mastro: Mansfield has lost two of its last four, including a heartbreaker on Thanksgiving. Duxbury hasn’t lost in years. Duxbury 28, Mansfield 7.

Division 2A
No. 8 Burlington (10-1) at No. 7 Beverly (11-0), 7:45:
Anthony: It’s a heavyweight tag team match here – Beverly’s pair of running backs, Brendan Flaherty and Kenny Pierce, against Burlington’s Marcus Odiah and Anthony Cruz. These teams are capable of slugging it out punch for punch, but I think Beverly can pull out the late stops and squeeze this out. Beverly 20, Burlington 16.
Mastro: This is really as close as it gets on paper. What’s stronger, the Middlesex League or the CAL/NEC? Beverly 29, Burlington 13.

No. 19 Plymouth South (8-3) vs. No. 6 Natick (10-1), at Braintree, 7:45:
Anthony: By now, it’s clear what Natick’s pass-and-catch combo of Troy Flutie and Brian Dunlap is capable of. The Redhawks beat Walpole 21-14, and then Framingham 26-14 on Thanksgiving to get to this game, and their run won’t stop here. Natick 28, Plymouth South 21.
Mastro: I’m not discounting Plymouth South, but c’mon, it’s Natick. It’s Flutie. It’s Dunlap. It’s touchdowns. A lot of them. Natick 35, Plymouth South 22.

Division 3
No. 20 Westwood (8-3) vs. Wayland (8-3) at Reading, 5:15:
Anthony: Westwood shocked Holliston with a 42-12 victory on Thanksgiving to punch its ticket to the playoffs. Why stop there? Westwood 22, Wayland 16.
Mastro: Robert Williams is rushing for 5 yards a carry and Wayland has averaged 28 points over a four-game win streak. Give me the DCL-tested team. Wayland 21, Westwood 14.

Sharon (8-3) vs. Pembroke (7-3), at Braintree, 5:15:
Anthony: Will we see the Sharon team that beat Stoughton (9-2), or the one that lost to Oliver Ames 35-7 on Thanksgiving? I can’t seem to figure it out, so I’m siding with Pembroke in this one. Pembroke 25, Sharon 18.
Mastro: Whether they’re winning these games or not, the Sharon kids have had to get their bodies smacked around by the likes of Stoughton, Foxboro and King Philip. The Hockomock has been so tough this year it makes any team ready for the playoffs. Sharon 21, Pembroke 19.

Division 3A
Lynnfield (8-2) vs. Amesbury (9-2), at Cawley Stadium, 5:15:
Mastro: Neil Weidman has done a nice job with this Lynnfield program, which is averaging seven wins a season since he arrived five years ago. He’s getting the hang of this. Lynnfield 15, Amesbury 7.
Anthony: In Week 2, Amesbury held a 27-12 lead against Lynnfield before the Pioneers rattled off 19 points and came away with a 31-27 win. If the Indians learned anything, it’s that they can’t sit on a lead. Amesbury 21, Lynnfield 13.

Dighton-Rehoboth (9-1) vs. Bishop Feehan (8-2), at Taunton, 7:45:
Mastro: Always love a team that plays up, and Feehan’s only two losses have come to Attleboro and North Attleboro in a pair of close, defensive battles. The Shamrocks are averaging 6.5 points allowed per game. Bishop Feehan 21, Dighton-Rehoboth 0.
Anthony: Running back Matt Allen can motor, and he’s scored seven touchdowns in the last three game to lead Bishop Feehan down the stretch. Can Allen keep his wheels spinning against D-R? Bishop Feehan 28, Dighton-Rehoboth 22.

Division 4
Shawsheen (9-1) vs. St. Mary’s (10-1), Manning Field, 5:15:
Mastro: Two high-powered offenses. One high-powered defense. St. Mary’s 34, Shawsheen 14.
Anthony: Both teams bring electric offensive attacks, but Shawsheen has held opponents to single-digit scoring just twice this season, which might spell trouble against the Spartans. St. Mary’s 30, Shawsheen 22.

No. 18 Abington (11-0) vs. Millis-Hopedale (8-3), at Bridgewater-Raynham, 5:15:
Mastro: How good has Abington been? So good that coach Jim Kelliher may not retire afterward, as he originally planned after his wife, Elaine, died in April. Kelliher has had some of his finest seasons of late, leading the Green Wave to a Super Bowl title in ’02 and ’05. He deserves a third. Abington 28, Millis-Hopedale 7.
Anthony: From 6-5 last year, the undefeated Green Wave has completed one of the finer turnarounds in Eastern Mass. They’ve shown their ability to score, averaging 29.7 points per game, and they can win the tight games, too. Abington 22, Millis-Hopedale 16.

Division 4A
North Shore (8-3) vs. Cathedral (9-2), at Burlington, 5:15:
Mastro: With sophomore Kejonte Hickman at quarterback and senior Kadeem Edge catching passes, Cathedral has put up almost 30 points a game. Cathedral 28, North Shore 14.
Anthony: Vincent Burton isn’t the only running back in Div. 4A. North Shore running back Ross Murphy (17 touchdowns) can find paydirt as well, and he’ll help his team get to the 4A Super Bowl contests. North Shore 27, Cathedral 21.

Bristol-Plymouth (5-6) vs. Madison Park (7-4), at Weymouth, 5:15:
Mastro: You got to believe! Roosevelt Robinson is going to give the best pregame speech he’s ever given and the Falcons soar to the Super Bowl. Madison Park 19, Bristol-Plymouth 13.
Anthony: Madison Park is coming off two-straight losses to end the season, while Bristol-Plymouth is riding a 28-26 win over Blue Hills. The Craftsmen will make the most out of their first playoff run since 2009. Bristol-Plymouth 14, Madison Park 6.